Leg length, sitting height and postmenopausal breast cancer risk

BACKGROUND: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS: From the prospective Danish cohort ‘Diet, Cancer and Health’, 23 864 postmenopausal women enrolled...

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Autores principales: Mellemkjær, L, Christensen, J, Frederiksen, K, Baker, J L, Olsen, A, Sørensen, T I A, Tjønneland, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389429/
https://www.ncbi.nlm.nih.gov/pubmed/22677900
http://dx.doi.org/10.1038/bjc.2012.244
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author Mellemkjær, L
Christensen, J
Frederiksen, K
Baker, J L
Olsen, A
Sørensen, T I A
Tjønneland, A
author_facet Mellemkjær, L
Christensen, J
Frederiksen, K
Baker, J L
Olsen, A
Sørensen, T I A
Tjønneland, A
author_sort Mellemkjær, L
collection PubMed
description BACKGROUND: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS: From the prospective Danish cohort ‘Diet, Cancer and Health’, 23 864 postmenopausal women enrolled during 1993–1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. RESULTS: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06–1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01–1.17) and 1.14 (95% CI=1.04–1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). CONCLUSION: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.
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spelling pubmed-33894292013-06-26 Leg length, sitting height and postmenopausal breast cancer risk Mellemkjær, L Christensen, J Frederiksen, K Baker, J L Olsen, A Sørensen, T I A Tjønneland, A Br J Cancer Short Communication BACKGROUND: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS: From the prospective Danish cohort ‘Diet, Cancer and Health’, 23 864 postmenopausal women enrolled during 1993–1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. RESULTS: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06–1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01–1.17) and 1.14 (95% CI=1.04–1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). CONCLUSION: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height. Nature Publishing Group 2012-06-26 2012-06-07 /pmc/articles/PMC3389429/ /pubmed/22677900 http://dx.doi.org/10.1038/bjc.2012.244 Text en Copyright © 2012 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Short Communication
Mellemkjær, L
Christensen, J
Frederiksen, K
Baker, J L
Olsen, A
Sørensen, T I A
Tjønneland, A
Leg length, sitting height and postmenopausal breast cancer risk
title Leg length, sitting height and postmenopausal breast cancer risk
title_full Leg length, sitting height and postmenopausal breast cancer risk
title_fullStr Leg length, sitting height and postmenopausal breast cancer risk
title_full_unstemmed Leg length, sitting height and postmenopausal breast cancer risk
title_short Leg length, sitting height and postmenopausal breast cancer risk
title_sort leg length, sitting height and postmenopausal breast cancer risk
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389429/
https://www.ncbi.nlm.nih.gov/pubmed/22677900
http://dx.doi.org/10.1038/bjc.2012.244
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