Cargando…

Mathematical Insights into the Effects of Levodopa

Parkinson’s disease has been traditionally thought of as a dopaminergic disease in which cells of the substantia nigra pars compacta (SNc) die. However, accumulating evidence implies an important role for the serotonergic system in Parkinson’s disease in general and in physiological responses to lev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reed, Michael C., Nijhout, H. Frederik, Best, Janet A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389445/ https://www.ncbi.nlm.nih.gov/pubmed/22783173 http://dx.doi.org/10.3389/fnint.2012.00021

Ejemplares similares

Serotonin synthesis, release and reuptake in terminals: a mathematical model
por: Best, Janet, et al.
Publicado: (2010)

Computational studies of the role of serotonin in the basal ganglia
por: Reed, Michael C., et al.
Publicado: (2013)

Using mathematical models to understand metabolism, genes, and disease
por: Nijhout, H. Frederik, et al.
Publicado: (2015)

Homeostatic mechanisms in dopamine synthesis and release: a mathematical model
por: Best, Janet A, et al.
Publicado: (2009)

Mathematical model insights into arsenic detoxification
por: Lawley, Sean D, et al.
Publicado: (2011)

A mathematical model for histamine synthesis, release, and control in varicosities
por: Best, Janet, et al.
Publicado: (2017)

In vivo Hippocampal Serotonin Dynamics in Male and Female Mice: Determining Effects of Acute Escitalopram Using Fast Scan Cyclic Voltammetry
por: Saylor, Rachel A., et al.
Publicado: (2019)

Corrigendum: In vivo Hippocampal Serotonin Dynamics in Male and Female Mice: Determining Effects of Acute Escitalopram Using Fast Scan Cyclic Voltammetry
por: Saylor, Rachel A., et al.
Publicado: (2019)

Mathematical analysis of the regulation of competing methyltransferases
por: Reed, Michael C., et al.
Publicado: (2015)

Mathematical modeling of the effects of glutathione on arsenic methylation
por: Lawley, Sean D, et al.
Publicado: (2014)

A mathematical model of glutathione metabolism
por: Reed, Michael C, et al.
Publicado: (2008)

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model
por: Ben-Shachar, Rotem, et al.
Publicado: (2012)

Autoreceptor control of serotonin dynamics
por: Best, Janet, et al.
Publicado: (2020)

A Mathematical Model of Levodopa Medication Effect on Basal Ganglia in Parkinson's Disease: An Application to the Alternate Finger Tapping Task
por: Baston, Chiara, et al.
Publicado: (2016)

A new mathematical approach for qualitative modeling of the insulin-TOR-MAPK network
por: Nijhout, H. Frederik, et al.
Publicado: (2013)

Maladaptive Plasticity in Levodopa-Induced Dyskinesias and Tardive Dyskinesias: Old and New Insights on the Effects of Dopamine Receptor Pharmacology
por: Cerasa, Antonio, et al.
Publicado: (2014)

Effect of Acute Levodopa Up-Titration on Blood Pressure in Patients With Early Stage Parkinson’s Disease: Results of a Levodopa Challenge Test
por: He, Xiaoqin, et al.
Publicado: (2022)

“Cueing” for Levodopa-Induced Dyskinesias in Parkinson’s Disease
por: Schaeffer, Eva, et al.
Publicado: (2016)

Parkinson's Disease: General Features, Effects of Levodopa Treatment and Future Directions
por: Freire, Marco Aurélio M., et al.
Publicado: (2010)

Effect of Levodopa on Reward and Impulsivity in a Rat Model of Parkinson’s Disease
por: Carvalho, Miguel M., et al.
Publicado: (2017)

Effects of combined MAO-B inhibitors and levodopa vs. monotherapy in Parkinson’s disease
por: Krishna, Rakhee, et al.
Publicado: (2014)

Differential Influence of Levodopa on Reward-Based Learning in Parkinson's Disease
por: Graef, Susanne, et al.
Publicado: (2010)

Future Scenarios for Levodopa-Induced Dyskinesias in Parkinson’s Disease
por: Cerasa, Antonio, et al.
Publicado: (2015)

One-carbon metabolism during the menstrual cycle and pregnancy
por: Kim, Ruby, et al.
Publicado: (2021)

Basal Ganglia Circuits Underlying the Pathophysiology of Levodopa-Induced Dyskinesia
por: Barroso-Chinea, Pedro, et al.
Publicado: (2010)

Cerebellum in Levodopa-Induced Dyskinesias: The Unusual Suspect in the Motor Network
por: Kishore, Asha, et al.
Publicado: (2014)

Additive Effects of Levodopa and a Neurorestorative Diet in a Mouse Model of Parkinson’s Disease
por: Perez-Pardo, Paula, et al.
Publicado: (2018)

Levodopa-Induced Changes in Electromyographic Patterns in Patients with Advanced Parkinson’s Disease
por: Ruonala, Verneri, et al.
Publicado: (2018)

A Population Model of Folate-Mediated One-Carbon Metabolism
por: Duncan, Tanya M., et al.
Publicado: (2013)

Spiracular fluttering increases oxygen uptake
por: Lawley, Sean D., et al.
Publicado: (2020)

Effects of levodopa on gut bacterial antibiotic resistance in Parkinson’s disease rat
por: Sheng, Shuo, et al.
Publicado: (2023)

Neuroanatomical and Microglial Alterations in the Striatum of Levodopa-Treated, Dyskinetic Hemi-Parkinsonian Rats
por: Fletcher, Edward J. R., et al.
Publicado: (2020)

Levodopa Enhances Reward Learning but Impairs Reversal Learning in Parkinson's Disease Patients
por: Moustafa, Ahmed A.
Publicado: (2011)

What Mechanisms Are Responsible for the Reuptake of Levodopa-Derived Dopamine in Parkinsonian Striatum?
por: Nishijima, Haruo, et al.
Publicado: (2016)

Nigral Iron Deposition Is Associated With Levodopa-Induced Dyskinesia in Parkinson’s Disease
por: Song, Tianbin, et al.
Publicado: (2021)

Speech and Voice Response to a Levodopa Challenge in Late-Stage Parkinson’s Disease
por: Fabbri, Margherita, et al.
Publicado: (2017)

Brain-Region Specific Metabolic Abnormalities in Parkinson’s Disease and Levodopa-Induced Dyskinesia
por: Yang, Changwei, et al.
Publicado: (2020)

A Multi-Scale Computational Model of Levodopa-Induced Toxicity in Parkinson's Disease
por: Muddapu, Vignayanandam Ravindernath-Jayashree, et al.
Publicado: (2022)

Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming
por: Nakamura, Takashi, et al.
Publicado: (2023)

An In Vivo Definition of Brain Histamine Dynamics Reveals Critical Neuromodulatory Roles for This Elusive Messenger
por: Berger, Shane N., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qacsi620tok8cuqh5httijifu1