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In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system
Although significant progress has been made in understanding the importance of Wnt signaling in the initiation of colorectal cancer, less is known about responses that accompany the reversal of oncogenic Wnt signaling. The aim of this study was to analyze in vivo and in vitro responses to an ‘ideal’...
Autores principales: | Jardé, Thierry, Evans, Rebecca J, McQuillan, Karina L, Parry, Lee, Feng, Gui Jie, Alvares, Bernardo, Clarke, Alan R, Dale, Trevor C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389516/ https://www.ncbi.nlm.nih.gov/pubmed/22469981 http://dx.doi.org/10.1038/onc.2012.103 |
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