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The H19 lincRNA is a developmental reservoir of miR-675 which suppresses growth and Igf1r
The H19 large intergenic noncoding RNA (lincRNA) is one of the most highly abundant and conserved transcripts in mammalian development, being expressed in both embryonic and extraembryonic cell lineages, yet its physiological function is unknown. Here we show that miR-675, a microRNA (miRNA) embedde...
Autores principales: | Keniry, Andrew, Oxley, David, Monnier, Paul, Kyba, Michael, Dandolo, Luisa, Smits, Guillaume, Reik, Wolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389517/ https://www.ncbi.nlm.nih.gov/pubmed/22684254 http://dx.doi.org/10.1038/ncb2521 |
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