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Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity
The protein kinase C-θ (PKCθ), which is essential for T cell function and survival, is also required for efficient anti-tumor immune surveillance. Natural killer (NK) cells, which express PKCθ, play a prominent role in this process, mainly by elimination of tumor cells with reduced or absent major h...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389606/ https://www.ncbi.nlm.nih.gov/pubmed/22783260 http://dx.doi.org/10.3389/fimmu.2012.00187 |