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The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway
The A2A adenosine receptor (A2AR)-mediated immunosuppression is firmly implicated in the life-saving down-regulation of collateral tissue damage during the anti-pathogen immune response and in highly undesirable protection of cancerous tissues during anti-tumor immune response. Therefore, depending...
Autores principales: | Ohta, Akio, Kini, Radhika, Ohta, Akiko, Subramanian, Meenakshi, Madasu, Manasa, Sitkovsky, Michail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389649/ https://www.ncbi.nlm.nih.gov/pubmed/22783261 http://dx.doi.org/10.3389/fimmu.2012.00190 |
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