Cargando…

Toward an Integrative Computational Model of the Guinea Pig Cardiac Myocyte

The local control theory of excitation-contraction (EC) coupling asserts that regulation of calcium (Ca(2+)) release occurs at the nanodomain level, where openings of single L-type Ca(2+) channels (LCCs) trigger openings of small clusters of ryanodine receptors (RyRs) co-localized within the dyad. A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gauthier, Laura Doyle, Greenstein, Joseph L., Winslow, Raimond L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389778/ https://www.ncbi.nlm.nih.gov/pubmed/22783206 http://dx.doi.org/10.3389/fphys.2012.00244

Ejemplares similares

Grand Challenges in Computational Physiology and Medicine
por: Winslow, Raimond L.
Publicado: (2011)

Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue
por: Walker, Mark A., et al.
Publicado: (2017)

Frequency-dependent signaling in cardiac myocytes
por: Haftbaradaran Esfahani, Payam, et al.
Publicado: (2022)

Improving cardiac myocytes performance by carbon nanotubes platforms(†)
por: Martinelli, Valentina, et al.
Publicado: (2013)

Construction of Calcium Release Sites in Cardiac Myocytes
por: Zahradníková, Alexandra, et al.
Publicado: (2012)

Quantification of Myocyte Disarray in Human Cardiac Tissue
por: Giardini, Francesco, et al.
Publicado: (2021)

Sodium-activated Potassium Current in Guinea pig Gastric Myocytes
por: Kim, Young Chul, et al.
Publicado: (2007)

Predicting respiratory decompensation in mechanically ventilated adult ICU patients
por: Tan, Yvette, et al.
Publicado: (2023)

Systems biology approaches to understanding the cause and treatment of heart, lung, blood, and sleep disorders
por: Winslow, Raimond L.
Publicado: (2014)

Effects of external protons on single cardiac sodium channels from guinea pig ventricular myocytes
Publicado: (1991)

Demographic and Methodological Heterogeneity in Electrocardiogram Signals From Guinea Pigs
por: Haq, Kazi T., et al.
Publicado: (2022)

Editorial: Methods and applications in computational physiology and medicine
por: Khandoker, A. H., et al.
Publicado: (2022)

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology
por: Jæger, Karoline Horgmo, et al.
Publicado: (2021)

Computational Modeling and Numerical Methods for Spatiotemporal Calcium Cycling in Ventricular Myocytes
por: Nivala, Michael, et al.
Publicado: (2012)

Calcium Signaling and Contractility in Cardiac Myocyte of Wolframin Deficient Rats
por: Cagalinec, Michal, et al.
Publicado: (2019)

Regulatory Volume Decrease of Cardiac Myocytes Induced by β-Adrenergic Activation of the Cl(−) Channel in Guinea Pig
por: Wang, Zhuren, et al.
Publicado: (1997)

Critical Requirements for the Initiation of a Cardiac Arrhythmia in Rat Ventricle: How Many Myocytes?
por: Ullah, Aman, et al.
Publicado: (2022)

Guinea Pig Oxygen-Sensing and Carotid Body Functional Properties
por: Gonzalez-Obeso, Elvira, et al.
Publicado: (2017)

SERCA Activity Controls the Systolic Calcium Increase in the Nucleus of Cardiac Myocytes
por: Kiess, Tobias-Oliver, et al.
Publicado: (2019)

Mechano-Electric Coupling and Arrhythmogenic Current Generation in a Computational Model of Coupled Myocytes
por: Timmermann, Viviane, et al.
Publicado: (2020)

Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology
Publicado: (1994)

On the mechanism of rectification of the isoproterenol-activated chloride current in guinea-pig ventricular myocytes
Publicado: (1993)

Estimating ectopic beat probability with simplified statistical models that account for experimental uncertainty
por: Jin, Qingchu, et al.
Publicado: (2021)

TNFα Modulates Cardiac Conduction by Altering Electrical Coupling between Myocytes
por: George, Sharon A., et al.
Publicado: (2017)

Come Together: Protein Assemblies, Aggregates and the Sarcostat at the Heart of Cardiac Myocyte Homeostasis
por: Islam, Moydul, et al.
Publicado: (2020)

A Comorbidity Model of Myocardial Ischemia/Reperfusion Injury and Hypercholesterolemia in Rat Cardiac Myocyte Cultures
por: Makkos, András, et al.
Publicado: (2020)

Guinea Pig as a Model to Study the Carotid Body Mediated Chronic Intermittent Hypoxia Effects
por: Docio, Inmaculada, et al.
Publicado: (2018)

Contractile State Dependent Sarcomere Length Variability in Isolated Guinea-Pig Cardiomyocytes
por: Lookin, Oleg, et al.
Publicado: (2022)

The Changes of KCNQ5 Expression and Potassium Microenvironment in the Retina of Myopic Guinea Pigs
por: Yang, Qin, et al.
Publicado: (2021)

The Interplay of Rogue and Clustered Ryanodine Receptors Regulates Ca(2+) Waves in Cardiac Myocytes
por: Chen, Xudong, et al.
Publicado: (2018)

Long-Term Regulation of Excitation–Contraction Coupling and Oxidative Stress in Cardiac Myocytes by Pirfenidone
por: Monsalvo-Villegas, Adrián, et al.
Publicado: (2018)

Transcriptomic Coupling of PKP2 With Inflammatory and Immune Pathways Endogenous to Adult Cardiac Myocytes
por: Pérez-Hernández, Marta, et al.
Publicado: (2021)

TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder
por: Daugherty, Stephanie L., et al.
Publicado: (2021)

Benchmarking electrophysiological models of human atrial myocytes
por: Wilhelms, Mathias, et al.
Publicado: (2013)

Endostatin inhibits T-type Ca(2+) channel current in guinea pig ventricular myocyte
por: YASUDA, Jumpei, et al.
Publicado: (2015)

The Role of Ca(2+) Sparks in Force Frequency Relationships in Guinea Pig Ventricular Myocytes
por: Paudel, Roshan, et al.
Publicado: (2022)

Calcium Sensing Receptors Mediate Local Inhibitory Reflexes Evoked by L-Phenylalanine in Guinea Pig Jejunum
por: Gwynne, Rachel M., et al.
Publicado: (2017)

GPER limits adverse changes to Ca(2+) signalling and arrhythmogenic activity in ovariectomised guinea pig cardiomyocytes
por: Francis, Alice J., et al.
Publicado: (2022)

Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects
por: Smit, Nicoline W., et al.
Publicado: (2014)

Distinguishing between overdrive excited and suppressed ventricular beats in guinea pig ventricular myocardium
por: Greer-Short, Amara, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h0cor7cpvo9vdduvrnsll39bk0