Cargando…

Altered expression of γ-secretase components in animal model of major depressive disorder induced by reserpine administration

Altered expression of neurotrophic factors as well as neuroinflammation is commonly associated with Major depressive disorder (MDD) and Alzheimer's disease (AD). To investigate whether or not reserpine-induced MDD affects the expression of AD-related proteins, the expression of γ-secretase comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hye-Ryun, Hwang, In-Sik, Kim, Ji-Eun, Choi, Sun-Il, Lee, Young-Ju, Goo, Jun-Seo, Lee, Eon-Pil, Choi, Hae-Wook, Kim, Hong-Sung, Lee, Jae-Ho, Jung, Young-Jin, Hwang, Dae-Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Association for Laboratory Animal Science 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389834/ https://www.ncbi.nlm.nih.gov/pubmed/22787484 http://dx.doi.org/10.5625/lar.2012.28.2.109

Ejemplares similares

Peroxiredoxin I regulates the component expression of γ-secretase complex causing the Alzheimer's disease
por: Lee, Young Ju, et al.
Publicado: (2011)

Effects of Red Liriope platyphylla on NGF secretion ability, NGF receptor signaling pathway and γ-secretase components in NSE/hAPPsw transgenic mice expressing Alzheimer's Disease
por: Choi, Sun-Il, et al.
Publicado: (2012)

Antidepressant and Anxiolytic-Like Effects of the Stem Bark Extract of Fraxinus rhynchophylla Hance and Its Components in a Mouse Model of Depressive-Like Disorder Induced by Reserpine Administration
por: Kim, Yu Ri, et al.
Publicado: (2021)

Effects of Steaming Time and Frequency for Manufactured Red Liriope platyphylla on the Insulin Secretion Ability and Insulin Receptor Signaling Pathway
por: Choi, Sun Il, et al.
Publicado: (2011)

γ-Secretase Components as Predictors of Breast Cancer Outcome
por: Peltonen, Hanna M., et al.
Publicado: (2013)

Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats
por: Kim, Ji-Eun, et al.
Publicado: (2012)

Monitoring of antibiotic resistance in bacteria isolated from laboratory animals
por: Goo, Jun-Seo, et al.
Publicado: (2012)

Antidepressant-Like Effects of Gyejibokryeong-hwan in a Mouse Model of Reserpine-Induced Depression
por: Park, Bo-Kyung, et al.
Publicado: (2018)

Overexpression of Insulin Degrading Enzyme could Greatly Contribute to Insulin Down-regulation Induced by Short-Term Swimming Exercise
por: Kim, Min Sun, et al.
Publicado: (2011)

Evaluation of the prognostic significances of γ-secretase genes in pancreatic cancer
por: Jeon, Yun Ho, et al.
Publicado: (2019)

Toxicity of red Liriope platyphylla manufactured by steaming process on liver and kidney organs of ICR mice
por: Choi, Sun-Il, et al.
Publicado: (2012)

Usefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children
por: Yun, Ki Wook, et al.
Publicado: (2016)

Overexpression of N141I PS2 increases γ-secretase activity through up-regulation of Presenilin and Pen-2 in brain mitochondria of NSE/hPS2m transgenic mice
por: Yun, Woo Bin, et al.
Publicado: (2016)

Structure of the transmembrane domain of human nicastrin-a component of γ-secretase
por: Li, Yan, et al.
Publicado: (2016)

Substrate docking to γ-secretase allows access of γ-secretase modulators to an allosteric site
por: Uemura, Kengo, et al.
Publicado: (2010)

Presenilin/γ-Secretase and Inflammation
por: Saura, Carlos A.
Publicado: (2010)

γ-Secretase in Alzheimer’s disease
por: Hur, Ji-Yeun
Publicado: (2022)

The effects of reserpine on depression: A systematic review
por: Strawbridge, Rebecca, et al.
Publicado: (2022)

Biogenesis of γ-secretase early in the secretory pathway
por: Kim, Jinoh, et al.
Publicado: (2007)

γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not
por: Lessard, Christian B., et al.
Publicado: (2020)

γ‐Secretase modulators show selectivity for γ‐secretase–mediated amyloid precursor protein intramembrane processing
por: Weber, Tobias A., et al.
Publicado: (2021)

Amylin and pramlintide modulate γ-secretase level and APP processing in lipid rafts
por: Mousa, Youssef M., et al.
Publicado: (2020)

Structure-function relationship of γ-secretase
por: Tomita, Taisuke
Publicado: (2012)

The dynamic conformational landscape of γ-secretase
por: Elad, Nadav, et al.
Publicado: (2015)

Presenilins and γ-Secretase in Membrane Proteostasis
por: Oikawa, Naoto, et al.
Publicado: (2019)

The cytotoxicity of γ-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by γ-secretase inhibition
por: Han, Jianxun, et al.
Publicado: (2009)

Complex Relationships between Substrate Sequence and Sensitivity to Alterations in γ-Secretase Processivity Induced by γ-Secretase Modulators
por: Jung, Joo In, et al.
Publicado: (2014)

COLORIMETRIC DETERMINATION OF RESERPINE IN POLYHERBAL FORMULATIONS
por: Azan, Md. Afzal, et al.
Publicado: (1997)

Development of a High-Throughput Assay for Screening of γ-Secretase Inhibitor with Endogenous Human, Mouse or Drosophila γ-Secretase
por: Wang, Lie-Feng, et al.
Publicado: (2009)

Promotion of the inflammatory response in mid colon of complement component 3 knockout mice
por: Choi, Yun Ju, et al.
Publicado: (2022)

Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics
por: Choi, Yun Ju, et al.
Publicado: (2021)

Effects of γ-secretase inhibitors in mouse colon
Publicado: (2012)

Mechanism of Intramembrane Cleavage of Alcadeins by γ-Secretase
por: Piao, Yi, et al.
Publicado: (2013)

Structural basis of human γ-secretase assembly
por: Sun, Linfeng, et al.
Publicado: (2015)

γ-Secretase: a multifaceted regulator of angiogenesis
por: Boulton, Michael E, et al.
Publicado: (2008)

The γ-secretase complex: from structure to function
por: Zhang, Xian, et al.
Publicado: (2014)

γ‐Secretase Dependent Nuclear Targeting of Dystroglycan
por: Leocadio, Daniel, et al.
Publicado: (2016)

Mechanisms of γ-Secretase Activation and Substrate Processing
por: Bhattarai, Apurba, et al.
Publicado: (2020)

Enzyme–substrate interface targeting by imidazole‐based γ‐secretase modulators activates γ‐secretase and stabilizes its interaction with APP
por: Petit, Dieter, et al.
Publicado: (2022)

Red Liriope platyphylla stimulated the insulin secretion through the regulation of calcium concentration in rat insulinoma cells and animal models
por: Lee, Hye-Ryun, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_011k7bfh8u45al9mvb8ii5qhur