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C-Jun N-Terminal Kinase 2 Promotes Liver Injury via the Mitochondrial Permeability Transition after Hemorrhage and Resuscitation

Hemorrhagic shock leads to hepatic hypoperfusion and activation of mitogen-activated stress kinases (MAPK) like c-Jun N-terminal kinase (JNK) 1 and 2. Our aim was to determine whether mitochondrial dysfunction leading to hepatic necrosis and apoptosis after hemorrhage/resuscitation (H/R) was depende...

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Detalles Bibliográficos
Autores principales:	Czerny, Christoph, Theruvath, Tom P., Maldonado, Eduardo N., Lehnert, Mark, Marzi, Ingo, Zhong, Zhi, Lemasters, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390051/ https://www.ncbi.nlm.nih.gov/pubmed/22791932 http://dx.doi.org/10.1155/2012/641982

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