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Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population

BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use...

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Detalles Bibliográficos
Autores principales: Yao, Dao-Kuo, Wang, Le-Xin, Curran, Shane, Ball, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390085/
https://www.ncbi.nlm.nih.gov/pubmed/22783291
http://dx.doi.org/10.3724/SP.J.1263.2011.00088
Descripción
Sumario:BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). CONCLUSIONS: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.