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Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390085/ https://www.ncbi.nlm.nih.gov/pubmed/22783291 http://dx.doi.org/10.3724/SP.J.1263.2011.00088 |
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author | Yao, Dao-Kuo Wang, Le-Xin Curran, Shane Ball, Patrick |
author_facet | Yao, Dao-Kuo Wang, Le-Xin Curran, Shane Ball, Patrick |
author_sort | Yao, Dao-Kuo |
collection | PubMed |
description | BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). CONCLUSIONS: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications. |
format | Online Article Text |
id | pubmed-3390085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Science Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-33900852012-07-10 Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population Yao, Dao-Kuo Wang, Le-Xin Curran, Shane Ball, Patrick J Geriatr Cardiol Research Articles BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). CONCLUSIONS: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications. Science Press 2011-06 /pmc/articles/PMC3390085/ /pubmed/22783291 http://dx.doi.org/10.3724/SP.J.1263.2011.00088 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission. |
spellingShingle | Research Articles Yao, Dao-Kuo Wang, Le-Xin Curran, Shane Ball, Patrick Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title | Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title_full | Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title_fullStr | Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title_full_unstemmed | Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title_short | Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population |
title_sort | adherence to treatment guidelines in the pharmacological management of chronic heart failure in an australian population |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390085/ https://www.ncbi.nlm.nih.gov/pubmed/22783291 http://dx.doi.org/10.3724/SP.J.1263.2011.00088 |
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