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Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population

BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use...

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Detalles Bibliográficos
Autores principales: Yao, Dao-Kuo, Wang, Le-Xin, Curran, Shane, Ball, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390085/
https://www.ncbi.nlm.nih.gov/pubmed/22783291
http://dx.doi.org/10.3724/SP.J.1263.2011.00088
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author Yao, Dao-Kuo
Wang, Le-Xin
Curran, Shane
Ball, Patrick
author_facet Yao, Dao-Kuo
Wang, Le-Xin
Curran, Shane
Ball, Patrick
author_sort Yao, Dao-Kuo
collection PubMed
description BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). CONCLUSIONS: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications.
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spelling pubmed-33900852012-07-10 Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population Yao, Dao-Kuo Wang, Le-Xin Curran, Shane Ball, Patrick J Geriatr Cardiol Research Articles BACKGROUND: To document the pharmacotherapy of chronic heart failure (CHF) and to evaluate the adherence to treatment guidelines in Australian population. METHODS: The pharmacological management of 677 patients (female 46.7%, 75.5 ± 11.6 years) with CHF was retrospectively analyzed. RESULTS: The use of angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARB) and β-blockers were 58.2 % and 34.7 %, respectively. Major reasons for non-use of ACE inhibitors/ARBs were hyperkalemia and elevated serum creatinine level. For patients who did not receive β-blockers, asthma and chronic obstructive pulmonary disease were the main contraindications. Treatment at or above target dosages for ACE inhibitors/ARBs and β-blockers was low for each medication (40.3% and 28.9%, respectively). CONCLUSIONS: Evidenced-based medical therapies for heart failure were under used in a rural patient population. Further studies are required to develop processes to improve the optimal use of heart failure medications. Science Press 2011-06 /pmc/articles/PMC3390085/ /pubmed/22783291 http://dx.doi.org/10.3724/SP.J.1263.2011.00088 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Research Articles
Yao, Dao-Kuo
Wang, Le-Xin
Curran, Shane
Ball, Patrick
Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title_full Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title_fullStr Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title_full_unstemmed Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title_short Adherence to treatment guidelines in the pharmacological management of chronic heart failure in an Australian population
title_sort adherence to treatment guidelines in the pharmacological management of chronic heart failure in an australian population
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390085/
https://www.ncbi.nlm.nih.gov/pubmed/22783291
http://dx.doi.org/10.3724/SP.J.1263.2011.00088
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