Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity

Alzheimer's disease (AD) is a neurodegenerative disease, one of whose major pathological hallmarks is the accumulation of amyloid plaques comprised of aggregated β-amyloid (Aβ) peptides. It is now recognized that soluble Aβ oligomers may lead to synaptic dysfunctions early in AD pathology prece...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hui, Megill, Andrea, He, Kaiwen, Kirkwood, Alfredo, Lee, Hey-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390164/
https://www.ncbi.nlm.nih.gov/pubmed/22792491
http://dx.doi.org/10.1155/2012/272374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390164/
https://www.ncbi.nlm.nih.gov/pubmed/22792491
http://dx.doi.org/10.1155/2012/272374

Ejemplares similares