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Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity

Alzheimer's disease (AD) is a neurodegenerative disease, one of whose major pathological hallmarks is the accumulation of amyloid plaques comprised of aggregated β-amyloid (Aβ) peptides. It is now recognized that soluble Aβ oligomers may lead to synaptic dysfunctions early in AD pathology prece...

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Detalles Bibliográficos
Autores principales:	Wang, Hui, Megill, Andrea, He, Kaiwen, Kirkwood, Alfredo, Lee, Hey-Kyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390164/ https://www.ncbi.nlm.nih.gov/pubmed/22792491 http://dx.doi.org/10.1155/2012/272374

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