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Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo

Malignant glioma is a severe cancer with a poor prognosis. Local occurrence and rare metastases of malignant glioma make it a suitable target for gene therapy. Several studies have demonstrated the importance of Src kinase in different cancers. However, these studies have focused mainly on Src-defic...

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Detalles Bibliográficos
Autores principales: Stedt, Hanna, Alasaarela, Laura, Samaranayake, Haritha, Pikkarainen, Jere, Määttä, Ann-Marie, Kholová, Ivana, Parker, Aaron S., Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390242/
https://www.ncbi.nlm.nih.gov/pubmed/23344000
http://dx.doi.org/10.1038/mtna.2012.13