Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B

BACKGROUND: Although the peptidyl-prolyl isomerase, cyclophilin-A (peptidyl-prolyl isomerase, PPIA), has been studied for decades in the context of its intracellular functions, its extracellular roles as a major contributor to both inflammation and multiple cancers have more recently emerged. A wide...

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Detalles Bibliográficos
Autores principales: Bahmed, Karim, Henry, Curtis, Holliday, Michael, Redzic, Jasmina, Ciobanu, Madalina, Zhang, Fengli, Weekes, Colin, Sclafani, Robert, DeGregori, James, Eisenmesser, Elan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390265/
https://www.ncbi.nlm.nih.gov/pubmed/22631225
http://dx.doi.org/10.1186/1475-2867-12-19

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