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Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya

BACKGROUND: Resistance to sulphadoxine-pyrimethamine (SP) in Plasmodium falciparum parasites is associated with mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes and has spread worldwide. SP remains the recommended drug for intermittent preventive treatment fo...

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Detalles Bibliográficos
Autores principales:	Iriemenam, Nnaemeka C, Shah, Monica, Gatei, Wangeci, van Eijk, Anna M, Ayisi, John, Kariuki, Simon, Vanden Eng, Jodi, Owino, Simon O, Lal, Ashima A, Omosun, Yusuf O, Otieno, Kephas, Desai, Meghna, ter Kuile, Feiko O, Nahlen, Bernard, Moore, Julie, Hamel, Mary J, Ouma, Peter, Slutsker, Laurence, Shi, Ya Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390272/ https://www.ncbi.nlm.nih.gov/pubmed/22540158 http://dx.doi.org/10.1186/1475-2875-11-134

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