Cargando…

ZIP8 expression in human proximal tubule cells, human urothelial cells transformed by Cd(+2) and As(+3) and in specimens of normal human urothelium and urothelial cancer

BACKGROUND: ZIP8 functions endogenously as a Zn(+2)/HCO(3)(-) symporter that can also bring cadmium (Cd(+2)) into the cell. It has also been proposed that ZIP8 participates in Cd-induced testicular necrosis and renal disease. In this study real-time PCR, western analysis, immunostaining and fluoresc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ajjimaporn, Amornpan, Botsford, Tom, Garrett, Scott H, Sens, Mary Ann, Zhou, Xu Dong, Dunlevy, Jane R, Sens, Donald A, Somji, Seema
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390278/ https://www.ncbi.nlm.nih.gov/pubmed/22550998 http://dx.doi.org/10.1186/1475-2867-12-16

Ejemplares similares

Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd(+2 )or As(+3 )transformed human urothelial cells
por: Somji, Seema, et al.
Publicado: (2011)

Zinc, Zinc Transporters, and Cadmium Cytotoxicity in a Cell Culture Model of Human Urothelium
por: Satarug, Soisungwan, et al.
Publicado: (2021)

Differential expression of human metallothionein isoform I mRNA in human proximal tubule cells exposed to metals.
por: Garrett, S H, et al.
Publicado: (1998)

Transformation of Human Urothelial Cells (UROtsa) by As(3+) and Cd(2+) Induces the Expression of Keratin 6a
por: Somji, Seema, et al.
Publicado: (2008)

Loss of N-Cadherin Expression in Tumor Transplants Produced From As(+3)- and Cd(+2)-Transformed Human Urothelial (UROtsa) Cell Lines
por: Sandquist, Elizabeth J., et al.
Publicado: (2016)

Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCl2.
por: Somji, S, et al.
Publicado: (1999)

Prediction of the Number of Activated Genes in Multiple Independent Cd(+2)- and As(+3)-Induced Malignant Transformations of Human Urothelial Cells (UROtsa)
por: Garrett, Scott H., et al.
Publicado: (2014)

The immortalized UROtsa cell line as a potential cell culture model of human urothelium.
por: Rossi, M R, et al.
Publicado: (2001)

Short and long term gene expression variation and networking in human proximal tubule cells when exposed to cadmium
por: Garrett, Scott H, et al.
Publicado: (2013)

Expression of the constitutive and inducible forms of heat shock protein 70 in human proximal tubule cells exposed to heat, sodium arsenite, and CdCl(2).
por: Somji, S, et al.
Publicado: (1999)

SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As(+3)- and Cd(+2)-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC
por: Slusser-Nore, Andrea, et al.
Publicado: (2016)

Cadherin Expression, Vectorial Active Transport, and Metallothionein Isoform 3 Mediated EMT/MET Responses in Cultured Primary and Immortalized Human Proximal Tubule Cells
por: Slusser, Andrea, et al.
Publicado: (2015)

The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers
por: Hoggarth, Zachary E., et al.
Publicado: (2018)

Expression of hsp 27, hsp 60, hsc 70, and hsp 70 stress response genes in cultured human urothelial cells (UROtsa) exposed to lethal and sublethal concentrations of sodium arsenite.
por: Rossi, Michael R, et al.
Publicado: (2002)

Exposure of human proximal tubule cells to cd2+, zn2+, and Cu2+ induces metallothionein protein accumulation but not metallothionein isoform 2 mRNA.
por: Garrett, S H, et al.
Publicado: (1998)

Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer
por: Soh, Maureen A, et al.
Publicado: (2011)

Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells
por: Kalyan, Gazal, et al.
Publicado: (2022)

Primary and Immortalized Cultures of Human Proximal Tubule Cells Possess Both Progenitor and Non-Progenitor Cells That Can Impact Experimental Results
por: Shrestha, Swojani, et al.
Publicado: (2023)

Human urothelial carcinoma cell response to Sunitinib malate therapy in vitro
por: Wen, Jin, et al.
Publicado: (2015)

Electrical and freeze-fracture analysis of the effects of ionic cadmium on cell membranes of human proximal tubule cells.
por: Hazen-Martin, D J, et al.
Publicado: (1993)

Pevonedistat Inhibits SOX2 Expression and Sphere Formation but Also Drives the Induction of Terminal Differentiation Markers and Apoptosis within Arsenite-Transformed Urothelial Cells
por: Mehus, Aaron A., et al.
Publicado: (2023)

STEERing an IDeA in Undergraduate Research at a Rural Research Intensive University
por: Sens, Donald A., et al.
Publicado: (2017)

miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition
por: Huang, Shirui, et al.
Publicado: (2021)

Metallothionein isoform 3 as a potential biomarker for human bladder cancer.
por: Sens, M A, et al.
Publicado: (2000)

Single‐cell transcriptomes of mouse bladder urothelium uncover novel cell type markers and urothelial differentiation characteristics
por: Li, Yan, et al.
Publicado: (2021)

Nuclear size measurement for distinguishing urothelial carcinomas from reactive urothelium on tissue sections
por: Poropatich, Kate, et al.
Publicado: (2016)

Diagnostic value comparison of CellDetect, fluorescent in situ hybridization (FISH), and cytology in urothelial carcinoma
por: Shang, Donghao, et al.
Publicado: (2021)

Significance of pigmented urothelial and non-urothelial cells in voided urine specimens: A case report and review
por: Kagan, Joseph Alan, et al.
Publicado: (2017)

Iron uptake by ZIP8 and ZIP14 in human proximal tubular epithelial cells
por: van Raaij, S. E. G., et al.
Publicado: (2019)

The Immunohistochemical Expression of SOX-10 in Urothelial Carcinoma and the Non Neoplastic Urothelium; and a Correlation with the Tumor Features
por: Amer, Samar, et al.
Publicado: (2022)

Role of HRTPT in kidney proximal epithelial cell regeneration: Integrative differential expression and pathway analyses using microarray and scRNA‐seq
por: Shrestha, Swojani, et al.
Publicado: (2021)

The inhibitory effect of silencing CDCA3 on migration and proliferation in bladder urothelial carcinoma
por: Shen, Dexin, et al.
Publicado: (2021)

Contamination Assessment and Potential Human Health Risks of Heavy Metals in Urban Soils from Grand Forks, North Dakota, USA
por: Saleem, Muhammad, et al.
Publicado: (2023)

Prognostic significance of platelet-to-lymphocyte ratio in urothelial carcinoma patients: a meta-analysis
por: Bao, Yuhai, et al.
Publicado: (2019)

Activation of PPARγ and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As(3+)-transformed UROtsa cells
por: Mehus, Aaron A., et al.
Publicado: (2020)

The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells
por: Voels, Brent, et al.
Publicado: (2017)

Arsenite Exposure to Human RPCs (HRTPT) Produces a Reversible Epithelial Mesenchymal Transition (EMT): In-Vitro and In-Silico Study
por: Singhal, Sonalika, et al.
Publicado: (2023)

Phospho-mTOR in non-tumour and tumour bladder urothelium: Pattern of expression and impact on urothelial bladder cancer patients
por: AFONSO, JULIETA, et al.
Publicado: (2014)

Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma
por: Jou, Yeong-Chin, et al.
Publicado: (2021)

Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway
por: Liao, Xiao-Zhong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vh8mqbdhhqsf994nv50oq16isk