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Antibacterial Activity and Mechanism of a Scorpion Venom Peptide Derivative In Vitro and In Vivo

BmKn2 is an antimicrobial peptide (AMP) characterized from the venom of scorpion Mesobuthus martensii Karsch by our group. In this study, Kn2-7 was derived from BmKn2 to improve the antibacterial activity and decrease hemolytic activity. Kn2-7 showed increased inhibitory activity against both Gram-p...

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Detalles Bibliográficos
Autores principales: Cao, Luyang, Dai, Chao, Li, Zhongjie, Fan, Zheng, Song, Yu, Wu, Yingliang, Cao, Zhijian, Li, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390344/
https://www.ncbi.nlm.nih.gov/pubmed/22792229
http://dx.doi.org/10.1371/journal.pone.0040135