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Memantine Inhibits α3β2-nAChRs-Mediated Nitrergic Neurogenic Vasodilation in Porcine Basilar Arteries
Memantine, an NMDA receptor antagonist used for treatment of Alzheimer’s disease (AD), is known to block the nicotinic acetylcholine receptors (nAChRs) in the central nervous system (CNS). In the present study, we examined by wire myography if memantine inhibited α3β2-nAChRs located on cerebral peri...
Autores principales: | Lee, Reggie Hui-Chao, Tseng, Ting-Yi, Wu, Celeste Yin-Chieh, Chen, Po-Yi, Chen, Mei-Fang, Kuo, Jon-Son, Lee, Tony Jer-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390354/ https://www.ncbi.nlm.nih.gov/pubmed/22792283 http://dx.doi.org/10.1371/journal.pone.0040326 |
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