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Memantine Inhibits α3β2-nAChRs-Mediated Nitrergic Neurogenic Vasodilation in Porcine Basilar Arteries

Memantine, an NMDA receptor antagonist used for treatment of Alzheimer’s disease (AD), is known to block the nicotinic acetylcholine receptors (nAChRs) in the central nervous system (CNS). In the present study, we examined by wire myography if memantine inhibited α3β2-nAChRs located on cerebral peri...

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Detalles Bibliográficos
Autores principales: Lee, Reggie Hui-Chao, Tseng, Ting-Yi, Wu, Celeste Yin-Chieh, Chen, Po-Yi, Chen, Mei-Fang, Kuo, Jon-Son, Lee, Tony Jer-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390354/
https://www.ncbi.nlm.nih.gov/pubmed/22792283
http://dx.doi.org/10.1371/journal.pone.0040326

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