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TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans

TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia. To learn more about the normal biological and abnormal pathological role of this protein, we turned to Caenorhabditis elega...

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Detalles Bibliográficos
Autores principales:	Vaccaro, Alexandra, Tauffenberger, Arnaud, Ash, Peter E. A., Carlomagno, Yari, Petrucelli, Leonard, Parker, J. Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390363/ https://www.ncbi.nlm.nih.gov/pubmed/22792076 http://dx.doi.org/10.1371/journal.pgen.1002806

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