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FANCJ/BACH1 Acetylation at Lysine 1249 Regulates the DNA Damage Response
BRCA1 promotes DNA repair through interactions with multiple proteins, including CtIP and FANCJ (also known as BRIP1/BACH1). While CtIP facilitates DNA end resection when de-acetylated, the function of FANCJ in repair processing is less well defined. Here, we report that FANCJ is also acetylated. Pr...
Autores principales: | Xie, Jenny, Peng, Min, Guillemette, Shawna, Quan, Steven, Maniatis, Stephanie, Wu, Yuliang, Venkatesh, Aditya, Shaffer, Scott A., Brosh, Robert M., Cantor, Sharon B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390368/ https://www.ncbi.nlm.nih.gov/pubmed/22792074 http://dx.doi.org/10.1371/journal.pgen.1002786 |
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