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The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection
The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation. While there is limited information available on the roles of the classical and the alternative activation pa...
Autores principales: | Ali, Youssif M., Lynch, Nicholas J., Haleem, Kashif S., Fujita, Teizo, Endo, Yuichi, Hansen, Soren, Holmskov, Uffe, Takahashi, Kazue, Stahl, Gregory L., Dudler, Thomas, Girija, Umakhanth V., Wallis, Russell, Kadioglu, Aras, Stover, Cordula M., Andrew, Peter W., Schwaeble, Wilhelm J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390405/ https://www.ncbi.nlm.nih.gov/pubmed/22792067 http://dx.doi.org/10.1371/journal.ppat.1002793 |
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