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Genome-Wide Association Analysis in Asthma Subjects Identifies SPATS2L as a Novel Bronchodilator Response Gene

Bronchodilator response (BDR) is an important asthma phenotype that measures reversibility of airway obstruction by comparing lung function (i.e. FEV(1)) before and after the administration of a short-acting β(2)-agonist, the most common rescue medications used for the treatment of asthma. BDR also...

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Detalles Bibliográficos
Autores principales: Himes, Blanca E., Jiang, Xiaofeng, Hu, Ruoxi, Wu, Ann C., Lasky-Su, Jessica A., Klanderman, Barbara J., Ziniti, John, Senter-Sylvia, Jody, Lima, John J., Irvin, Charles G., Peters, Stephen P., Meyers, Deborah A., Bleecker, Eugene R., Kubo, Michiaki, Tamari, Mayumi, Nakamura, Yusuke, Szefler, Stanley J., Lemanske, Robert F., Zeiger, Robert S., Strunk, Robert C., Martinez, Fernando D., Hanrahan, John P., Koppelman, Gerard H., Postma, Dirkje S., Nieuwenhuis, Maartje A. E., Vonk, Judith M., Panettieri, Reynold A., Markezich, Amy, Israel, Elliot, Carey, Vincent J., Tantisira, Kelan G., Litonjua, Augusto A., Lu, Quan, Weiss, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390407/
https://www.ncbi.nlm.nih.gov/pubmed/22792082
http://dx.doi.org/10.1371/journal.pgen.1002824