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EGL-9 Controls C. elegans Host Defense Specificity through Prolyl Hydroxylation-Dependent and -Independent HIF-1 Pathways
Understanding host defense against microbes is key to developing new and more effective therapies for infection and inflammatory disease. However, how animals integrate multiple environmental signals and discriminate between different pathogens to mount specific and tailored responses remains poorly...
Autores principales: | Luhachack, Lyly G., Visvikis, Orane, Wollenberg, Amanda C., Lacy-Hulbert, Adam, Stuart, Lynda M., Irazoqui, Javier E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390412/ https://www.ncbi.nlm.nih.gov/pubmed/22792069 http://dx.doi.org/10.1371/journal.ppat.1002798 |
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