Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings

Malignant peripheral nerve sheath tumors (MPNST) represent a group of highly heterogeneous human malignancies often with multiple histological origins, divergent differentiation patterns, and diverse immunohistochemical presentations. The differential diagnosis of MPNST from other spindle cell neopl...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Aitao, Liu, Aijun, Wei, Lixin, Song, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Mini-Review/Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390600/
https://www.ncbi.nlm.nih.gov/pubmed/22773934
http://dx.doi.org/10.7150/jca.4179
_version_ 1782237457197039616
author Guo, Aitao
Liu, Aijun
Wei, Lixin
Song, Xin
author_facet Guo, Aitao
Liu, Aijun
Wei, Lixin
Song, Xin
author_sort Guo, Aitao
collection PubMed
description Malignant peripheral nerve sheath tumors (MPNST) represent a group of highly heterogeneous human malignancies often with multiple histological origins, divergent differentiation patterns, and diverse immunohistochemical presentations. The differential diagnosis of MPNST from other spindle cell neoplasms poses great challenges for pathologists. This report provides a mini-review of these unique features associated with MPNST and also presents the first cases of MPNST with six differentiation patterns.
format Online
Article
Text
id pubmed-3390600
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Ivyspring International Publisher
record_format MEDLINE/PubMed
spelling pubmed-33906002012-07-06 Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings Guo, Aitao Liu, Aijun Wei, Lixin Song, Xin J Cancer Mini-Review/Case Report Malignant peripheral nerve sheath tumors (MPNST) represent a group of highly heterogeneous human malignancies often with multiple histological origins, divergent differentiation patterns, and diverse immunohistochemical presentations. The differential diagnosis of MPNST from other spindle cell neoplasms poses great challenges for pathologists. This report provides a mini-review of these unique features associated with MPNST and also presents the first cases of MPNST with six differentiation patterns. Ivyspring International Publisher 2012-07-04 /pmc/articles/PMC3390600/ /pubmed/22773934 http://dx.doi.org/10.7150/jca.4179 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Mini-Review/Case Report
Guo, Aitao
Liu, Aijun
Wei, Lixin
Song, Xin
Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title_full Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title_fullStr Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title_full_unstemmed Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title_short Malignant Peripheral Nerve Sheath Tumors: Differentiation Patterns and Immunohistochemical Features - A Mini-Review and Our New Findings
title_sort malignant peripheral nerve sheath tumors: differentiation patterns and immunohistochemical features - a mini-review and our new findings
topic Mini-Review/Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390600/
https://www.ncbi.nlm.nih.gov/pubmed/22773934
http://dx.doi.org/10.7150/jca.4179
work_keys_str_mv AT guoaitao malignantperipheralnervesheathtumorsdifferentiationpatternsandimmunohistochemicalfeaturesaminireviewandournewfindings
AT liuaijun malignantperipheralnervesheathtumorsdifferentiationpatternsandimmunohistochemicalfeaturesaminireviewandournewfindings
AT weilixin malignantperipheralnervesheathtumorsdifferentiationpatternsandimmunohistochemicalfeaturesaminireviewandournewfindings
AT songxin malignantperipheralnervesheathtumorsdifferentiationpatternsandimmunohistochemicalfeaturesaminireviewandournewfindings

Ejemplares similares