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N–N Bond-Forming Cyclization for the One-Pot Synthesis of N-Aryl[3,4-d]pyrazolopyrimidines
[Image: see text] An efficient one-pot synthesis of N-aryl[3,4-d]pyrazolopyrimidines in good yield and under mild reaction conditions is described. By exploiting electron-deficient hydroxylamines, the substituted oxime products were formed with very high E-diastereoselectivity. The key step utilizes...
Autores principales: | Evans, Lindsay E., Cheeseman, Matthew D., Jones, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390909/ https://www.ncbi.nlm.nih.gov/pubmed/22734502 http://dx.doi.org/10.1021/ol301561a |
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