Formation of methotrexate-PLLA-PEG-PLLA composite microspheres by microencapsulation through a process of suspension-enhanced dispersion by supercritical CO(2)

BACKGROUND: The aim of this study was to improve the drug loading, encapsulation efficiency, and sustained-release properties of supercritical CO(2)-based drug-loaded polymer carriers via a process of suspension-enhanced dispersion by supercritical CO(2) (SpEDS), which is an advanced version of solu...

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Detalles Bibliográficos
Autores principales: Chen, Ai-Zheng, Wang, Guang-Ya, Wang, Shi-Bin, Li, Li, Liu, Yuan-Gang, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391004/
https://www.ncbi.nlm.nih.gov/pubmed/22787397
http://dx.doi.org/10.2147/IJN.S32662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391004/
https://www.ncbi.nlm.nih.gov/pubmed/22787397
http://dx.doi.org/10.2147/IJN.S32662

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