Cargando…

Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia

Records of 3,449 patients admitted to Karitas Hospital at Waitabula in eastern Indonesia with microscopy-confirmed malaria through 2008 and 2009 were systematically reviewed. Falciparum, vivax, and mixed species malaria occurred among 1,541, 1,837, and 71 admissions, respectively. Among these, 400 (...

Descripción completa

Detalles Bibliográficos
Autores principales: Nurleila, Siti, Syafruddin, Din, Elyazar, Iqbal R. F., Baird, J. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391056/
https://www.ncbi.nlm.nih.gov/pubmed/22764290
http://dx.doi.org/10.4269/ajtmh.2012.11-0577
_version_ 1782237483504762880
author Nurleila, Siti
Syafruddin, Din
Elyazar, Iqbal R. F.
Baird, J. Kevin
author_facet Nurleila, Siti
Syafruddin, Din
Elyazar, Iqbal R. F.
Baird, J. Kevin
author_sort Nurleila, Siti
collection PubMed
description Records of 3,449 patients admitted to Karitas Hospital at Waitabula in eastern Indonesia with microscopy-confirmed malaria through 2008 and 2009 were systematically reviewed. Falciparum, vivax, and mixed species malaria occurred among 1,541, 1,837, and 71 admissions, respectively. Among these, 400 (26%), 199 (11%), and 15 (21%) had serious illness. Fatalities occurred in 46 (12%), 18 (9%), and 2 (13%) of these patients, respectively. Although patients with a diagnosis of falciparum malaria were more likely to have serious illness compared with those with vivax malaria (odds ratio [OR] = 2.9; 95% confidence interval [CI]: 2.4–3.5), this diagnosis nonetheless was associated with 32% of serious illness and 27% of fatalities. Among the seriously ill with a diagnosis of falciparum or vivax malaria, no significant difference in risk of death occurred (OR = 1.3; 95% CI: 0.7–2.5). Serious and fatal illness was predominantly anemia or altered mental state syndromes among patients with either of the species diagnoses. Plasmodium vivax was associated with a substantial share of the burden of morbidity and mortality caused by malaria in this hypo- to meso-endemic community.
format Online
Article
Text
id pubmed-3391056
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher The American Society of Tropical Medicine and Hygiene
record_format MEDLINE/PubMed
spelling pubmed-33910562012-07-12 Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia Nurleila, Siti Syafruddin, Din Elyazar, Iqbal R. F. Baird, J. Kevin Am J Trop Med Hyg Articles Records of 3,449 patients admitted to Karitas Hospital at Waitabula in eastern Indonesia with microscopy-confirmed malaria through 2008 and 2009 were systematically reviewed. Falciparum, vivax, and mixed species malaria occurred among 1,541, 1,837, and 71 admissions, respectively. Among these, 400 (26%), 199 (11%), and 15 (21%) had serious illness. Fatalities occurred in 46 (12%), 18 (9%), and 2 (13%) of these patients, respectively. Although patients with a diagnosis of falciparum malaria were more likely to have serious illness compared with those with vivax malaria (odds ratio [OR] = 2.9; 95% confidence interval [CI]: 2.4–3.5), this diagnosis nonetheless was associated with 32% of serious illness and 27% of fatalities. Among the seriously ill with a diagnosis of falciparum or vivax malaria, no significant difference in risk of death occurred (OR = 1.3; 95% CI: 0.7–2.5). Serious and fatal illness was predominantly anemia or altered mental state syndromes among patients with either of the species diagnoses. Plasmodium vivax was associated with a substantial share of the burden of morbidity and mortality caused by malaria in this hypo- to meso-endemic community. The American Society of Tropical Medicine and Hygiene 2012-07-01 /pmc/articles/PMC3391056/ /pubmed/22764290 http://dx.doi.org/10.4269/ajtmh.2012.11-0577 Text en ©The American Society of Tropical Medicine and Hygiene http://creativecommons.org/licenses/by/2.5/ This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Nurleila, Siti
Syafruddin, Din
Elyazar, Iqbal R. F.
Baird, J. Kevin
Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title_full Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title_fullStr Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title_full_unstemmed Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title_short Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia
title_sort serious and fatal illness associated with falciparum and vivax malaria among patients admitted to hospital at west sumba in eastern indonesia
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391056/
https://www.ncbi.nlm.nih.gov/pubmed/22764290
http://dx.doi.org/10.4269/ajtmh.2012.11-0577
work_keys_str_mv AT nurleilasiti seriousandfatalillnessassociatedwithfalciparumandvivaxmalariaamongpatientsadmittedtohospitalatwestsumbaineasternindonesia
AT syafruddindin seriousandfatalillnessassociatedwithfalciparumandvivaxmalariaamongpatientsadmittedtohospitalatwestsumbaineasternindonesia
AT elyazariqbalrf seriousandfatalillnessassociatedwithfalciparumandvivaxmalariaamongpatientsadmittedtohospitalatwestsumbaineasternindonesia
AT bairdjkevin seriousandfatalillnessassociatedwithfalciparumandvivaxmalariaamongpatientsadmittedtohospitalatwestsumbaineasternindonesia