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Homeostatic Synaptic Scaling Is Regulated by Protein SUMOylation

Homeostatic scaling allows neurons to alter synaptic transmission to compensate for changes in network activity. Here, we show that suppression of network activity with tetrodotoxin, which increases surface expression of AMPA receptors (AMPARs), dramatically reduces levels of the deSUMOylating (wher...

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Detalles Bibliográficos
Autores principales:	Craig, Tim J., Jaafari, Nadia, Petrovic, Milos M., Rubin, Philip P., Mellor, Jack R., Henley, Jeremy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391081/ https://www.ncbi.nlm.nih.gov/pubmed/22582390 http://dx.doi.org/10.1074/jbc.M112.356337

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