Pathogen Sensing by Nucleotide-binding Oligomerization Domain-containing Protein 2 (NOD2) Is Mediated by Direct Binding to Muramyl Dipeptide and ATP

Nucleotide binding and oligomerization domain-containing protein 2 (NOD2/Card15) is an intracellular protein that is involved in the recognition of bacterial cell wall-derived muramyl dipeptide. Mutations in the gene encoding NOD2 are associated with inherited inflammatory disorders, including Crohn...

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Detalles Bibliográficos
Autores principales: Mo, Jinyao, Boyle, Joseph P., Howard, Christopher B., Monie, Tom P., Davis, Beckley K., Duncan, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391102/
https://www.ncbi.nlm.nih.gov/pubmed/22549783
http://dx.doi.org/10.1074/jbc.M112.344283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391102/
https://www.ncbi.nlm.nih.gov/pubmed/22549783
http://dx.doi.org/10.1074/jbc.M112.344283

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