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Low level genome mistranslations deregulate the transcriptome and translatome and generate proteotoxic stress in yeast
BACKGROUND: Organisms use highly accurate molecular processes to transcribe their genes and a variety of mRNA quality control and ribosome proofreading mechanisms to maintain intact the fidelity of genetic information flow. Despite this, low level gene translational errors induced by mutations and e...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391182/ https://www.ncbi.nlm.nih.gov/pubmed/22715922 http://dx.doi.org/10.1186/1741-7007-10-55 |