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Protection of Blood Retinal Barrier and Systemic Vasculature by Insulin-Like Growth Factor Binding Protein-3
Previously, we showed that insulin growth factor (IGF)-1 binding protein-3 (IGFBP-3), independent of IGF-1, reduces pathological angiogenesis in a mouse model of the oxygen-induced retinopathy (OIR). The current study evaluates novel endothelium-dependent functions of IGFBP-3 including blood retinal...
Autores principales: | Jarajapu, Yagna P. R., Cai, Jun, Yan, Yuanqing, Li Calzi, Sergio, Kielczewski, Jennifer L., Hu, Ping, Shaw, Lynn C., Firth, Sue M., Chan-Ling, Tailoi, Boulton, Michael E., Baxter, Robert C., Grant, Maria B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391198/ https://www.ncbi.nlm.nih.gov/pubmed/22792172 http://dx.doi.org/10.1371/journal.pone.0039398 |
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