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IL-1beta Signals through the EGF Receptor and Activates Egr-1 through MMP-ADAM

The immediate-early gene Egr-1 controls the inducible expression of many genes implicated in the pathogenesis of a range of vascular disorders, yet our understanding of the mechanisms controlling the rapid expression of this prototypic zinc finger transcription factor is poor. Here we show that Egr-...

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Detalles Bibliográficos
Autores principales: Sanchez-Guerrero, Estella, Chen, Elya, Kockx, Maaike, An, Si-Wei, Chong, Beng H., Khachigian, Levon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391205/
https://www.ncbi.nlm.nih.gov/pubmed/22792188
http://dx.doi.org/10.1371/journal.pone.0039811