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ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese
HLA-DRB1, especially the shared epitope (SE), is strongly associated with rheumatoid arthritis (RA). However, recent studies have shown that SE is at most weakly associated with RA without anti-citrullinated peptide/protein antibody (ACPA). We have recently reported that ACPA-negative RA is associat...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391228/ https://www.ncbi.nlm.nih.gov/pubmed/22792215 http://dx.doi.org/10.1371/journal.pone.0040067 |