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ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese

HLA-DRB1, especially the shared epitope (SE), is strongly associated with rheumatoid arthritis (RA). However, recent studies have shown that SE is at most weakly associated with RA without anti-citrullinated peptide/protein antibody (ACPA). We have recently reported that ACPA-negative RA is associat...

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Detalles Bibliográficos
Autores principales: Terao, Chikashi, Ohmura, Koichiro, Ikari, Katsunori, Kochi, Yuta, Maruya, Etsuko, Katayama, Masaki, Yurugi, Kimiko, Shimada, Kota, Murasawa, Akira, Honjo, Shigeru, Takasugi, Kiyoshi, Matsuo, Keitaro, Tajima, Kazuo, Suzuki, Akari, Yamamoto, Kazuhiko, Momohara, Shigeki, Yamanaka, Hisashi, Yamada, Ryo, Saji, Hiroo, Matsuda, Fumihiko, Mimori, Tsuneyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391228/
https://www.ncbi.nlm.nih.gov/pubmed/22792215
http://dx.doi.org/10.1371/journal.pone.0040067

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