Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS

TH17 cells enter tissues to facilitate pathogenic autoimmune responses, including multiple sclerosis (MS). However, the adhesion molecules involved in the unique migratory capacity of TH17 cells, into both inflamed and uninflamed tissues remain unclear. Herein, we characterize MCAM (CD146) as an adh...

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Detalles Bibliográficos
Autores principales: Flanagan, Ken, Fitzgerald, Kent, Baker, Jeanne, Regnstrom, Karin, Gardai, Shyra, Bard, Frederique, Mocci, Simonetta, Seto, Pui, You, Monica, Larochelle, Catherine, Prat, Alexandre, Chow, Samuel, Li, Lauri, Vandevert, Chris, Zago, Wagner, Lorenzana, Carlos, Nishioka, Christopher, Hoffman, Jennifer, Botelho, Raquel, Willits, Christopher, Tanaka, Kevin, Johnston, Jennifer, Yednock, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391262/
https://www.ncbi.nlm.nih.gov/pubmed/22792325
http://dx.doi.org/10.1371/journal.pone.0040443

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