The Role of LEF1 in Endometrial Gland Formation and Carcinogenesis

Endometrial carcinoma is the most common gynecologic cancer, yet the mechanisms underlying this disease process are poorly understood. We hypothesized that Lef1 is required for endometrial gland formation within the uterus and is overexpressed in endometrial cancer. Using Lef1 knockout (KO) mice, we...

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Detalles Bibliográficos
Autores principales: Shelton, Dawne N., Fornalik, Hubert, Neff, Traci, Park, Soo Yeun, Bender, David, DeGeest, Koen, Liu, Xiaoming, Xie, Weiliang, Meyerholz, David K., Engelhardt, John F., Goodheart, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391280/
https://www.ncbi.nlm.nih.gov/pubmed/22792274
http://dx.doi.org/10.1371/journal.pone.0040312

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