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Patient self-assessment of hospital pain, mood and health-related quality of life in adults with sickle cell disease
INTRODUCTION: Acute pain is a hallmark of sickle cell disease (SCD) for which frequent hospital admissions may be required, affecting the quality of life of patients. OBJECTIVES: To characterise the relationship between adult patient self-reported sickle cell pain, mood and quality of life during an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391376/ https://www.ncbi.nlm.nih.gov/pubmed/22761289 http://dx.doi.org/10.1136/bmjopen-2012-001274 |
Sumario: | INTRODUCTION: Acute pain is a hallmark of sickle cell disease (SCD) for which frequent hospital admissions may be required, affecting the quality of life of patients. OBJECTIVES: To characterise the relationship between adult patient self-reported sickle cell pain, mood and quality of life during and after hospital admissions. DESIGN: Longitudinal study across three time-points. SETTING: Secondary care, single specialist sickle cell centre. PARTICIPANTS: 510 adult patients with SCD admitted to hospital daycare or inpatient units. OUTCOME MEASURES: Self-assessments of pain, mood and health-related quality of life with health utility (measured on the EQ-5D) on admission, before discharge and at 1-week postdischarge. RESULTS: Mood, general health and quality of life showed significant steady improvements with reduction of pain in patients with SCD on admission to hospital, before discharge and at 1-week follow-up (p<0.01). Health utility scores derived from the EQ-5D showed a negative association with pain in regression analysis over the three time-points. CONCLUSION: Examining health-related quality of life and health utility in relation to pain during hospital admissions is valuable in terms of targeting appropriate psychological interventions within the context of a multidisciplinary approach to managing sickle cell pain. This has implications for healthcare costs. |
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