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Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study

OBJECTIVE: It is uncertain whether migraine prevalence has increased in modern society. The aim of this study was to assess any change in migraine prevalence over an 8-year period among the adult population in Denmark. DESIGN: Prospective longitudinal population-based study. SETTING: 30 000 twin ind...

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Autores principales: Le, Han, Tfelt-Hansen, Peer, Skytthe, Axel, Kyvik, Kirsten Ohm, Olesen, Jes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391377/
https://www.ncbi.nlm.nih.gov/pubmed/22761284
http://dx.doi.org/10.1136/bmjopen-2012-000962
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author Le, Han
Tfelt-Hansen, Peer
Skytthe, Axel
Kyvik, Kirsten Ohm
Olesen, Jes
author_facet Le, Han
Tfelt-Hansen, Peer
Skytthe, Axel
Kyvik, Kirsten Ohm
Olesen, Jes
author_sort Le, Han
collection PubMed
description OBJECTIVE: It is uncertain whether migraine prevalence has increased in modern society. The aim of this study was to assess any change in migraine prevalence over an 8-year period among the adult population in Denmark. DESIGN: Prospective longitudinal population-based study. SETTING: 30 000 twin individuals were invited to participate in two cross-sectional questionnaire surveys containing validated questions to diagnose migraine in 1994 and 2002. The twins are representative of the Danish population with regard to migraine and other somatic diseases. PARTICIPANTS: The 1994 cohort comprised 28 571 twin individuals aged 12–41 years and the 2002 cohort 31 865 twin individuals aged 20–71 years. OUTCOME MEASURES: Sex-, age- and subtype-specific incidence and lifetime prevalence as well as 1-year prevalence of migraine. RESULTS: 1-year prevalence in 2002 was 12.3% for migraine, 4.1% for migraine with aura and 8.2% for migraine without aura. Lifetime prevalence of migraine was 16.1% in 1994 (aged 12–41 years) and 25.2% in 2002 (aged 20–71 years). Lifetime prevalence of migraine for age 20–41 was increased from 1994 to 2002 (18.5% vs 24.5%) by 32.2% (95% CI 27.0% to 37.3%; p<0.001). The difference was primarily seen in the population older than 32 years. The increase was especially evident in migraine with aura (5.6% vs 9.4%, p<0.001) but also a significant increase in migraine without aura was found (13.0% vs 15.1%, p<0.001). Eight-year period incidence rate of migraine was 0.141 corresponding to an average annual incidence rate of 17.6 per 1000 person-years. CONCLUSIONS: Lifetime prevalence of migraine in Denmark increased substantially from 1994 to 2002. Part of the increase may be due to increased medical consultation resulting in increased rate of physician diagnosis or awareness due to previously participation in the 1994 survey. It is pertinent to study the environmental causes of the increase and to implement preventive measures.
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spelling pubmed-33913772012-07-10 Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study Le, Han Tfelt-Hansen, Peer Skytthe, Axel Kyvik, Kirsten Ohm Olesen, Jes BMJ Open Neurology OBJECTIVE: It is uncertain whether migraine prevalence has increased in modern society. The aim of this study was to assess any change in migraine prevalence over an 8-year period among the adult population in Denmark. DESIGN: Prospective longitudinal population-based study. SETTING: 30 000 twin individuals were invited to participate in two cross-sectional questionnaire surveys containing validated questions to diagnose migraine in 1994 and 2002. The twins are representative of the Danish population with regard to migraine and other somatic diseases. PARTICIPANTS: The 1994 cohort comprised 28 571 twin individuals aged 12–41 years and the 2002 cohort 31 865 twin individuals aged 20–71 years. OUTCOME MEASURES: Sex-, age- and subtype-specific incidence and lifetime prevalence as well as 1-year prevalence of migraine. RESULTS: 1-year prevalence in 2002 was 12.3% for migraine, 4.1% for migraine with aura and 8.2% for migraine without aura. Lifetime prevalence of migraine was 16.1% in 1994 (aged 12–41 years) and 25.2% in 2002 (aged 20–71 years). Lifetime prevalence of migraine for age 20–41 was increased from 1994 to 2002 (18.5% vs 24.5%) by 32.2% (95% CI 27.0% to 37.3%; p<0.001). The difference was primarily seen in the population older than 32 years. The increase was especially evident in migraine with aura (5.6% vs 9.4%, p<0.001) but also a significant increase in migraine without aura was found (13.0% vs 15.1%, p<0.001). Eight-year period incidence rate of migraine was 0.141 corresponding to an average annual incidence rate of 17.6 per 1000 person-years. CONCLUSIONS: Lifetime prevalence of migraine in Denmark increased substantially from 1994 to 2002. Part of the increase may be due to increased medical consultation resulting in increased rate of physician diagnosis or awareness due to previously participation in the 1994 survey. It is pertinent to study the environmental causes of the increase and to implement preventive measures. BMJ Group 2012-07-02 /pmc/articles/PMC3391377/ /pubmed/22761284 http://dx.doi.org/10.1136/bmjopen-2012-000962 Text en © 2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.
spellingShingle Neurology
Le, Han
Tfelt-Hansen, Peer
Skytthe, Axel
Kyvik, Kirsten Ohm
Olesen, Jes
Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title_full Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title_fullStr Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title_full_unstemmed Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title_short Increase in self-reported migraine prevalence in the Danish adult population: a prospective longitudinal population-based study
title_sort increase in self-reported migraine prevalence in the danish adult population: a prospective longitudinal population-based study
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391377/
https://www.ncbi.nlm.nih.gov/pubmed/22761284
http://dx.doi.org/10.1136/bmjopen-2012-000962
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