Lipid-Antigen Presentation by CD1d(+) B Cells Is Essential for the Maintenance of Invariant Natural Killer T Cells

B cells perform many immunological functions, including presenting lipid antigen to CD1d-restricted invariant natural killer T (iNKT) cells, known to contribute to maintaining tolerance in autoimmunity. Patients with systemic lupus erythematous (SLE) display dysregulated B cell responses and reduced...

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Detalles Bibliográficos
Autores principales: Bosma, Anneleen, Abdel-Gadir, Azza, Isenberg, David A., Jury, Elizabeth C., Mauri, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391684/
https://www.ncbi.nlm.nih.gov/pubmed/22406267
http://dx.doi.org/10.1016/j.immuni.2012.02.008

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