RNAi promotes heterochromatic silencing through replication-coupled release of RNA polII

Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes. The inheritance of heterochromatin through mitosis requires RNA interference (RNAi), which guides histone modification (1) during the DNA replication phase of the cell cycle(2). Here, we show that the alternati...

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Detalles Bibliográficos
Autores principales: Zaratiegui, Mikel, Castel, Stephane, Irvine, Danielle V., Kloc, Anna, Ren, Jie, Li, Fei, de Castro, Elisa, Marín, Laura, Chang, An-Yun, Goto, Derek, Cande, W. Zacheus, Antequera, Francisco, Arcangioli, Benoit, Martienssen, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391703/
https://www.ncbi.nlm.nih.gov/pubmed/22002604
http://dx.doi.org/10.1038/nature10501

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