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Hyponatremia – predictor of adverse prognosis in cirrhosis
Hyponatremia is a frequent complication of the advanced liver disease, being, as the hepatorenal syndrome, a consequence of the important circulatory dysfunction of cirrhosis. Hyponatremia is determined by the impaired capacity of the kidney to excrete free water, which leads to water retention disp...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Carol Davila University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391887/ https://www.ncbi.nlm.nih.gov/pubmed/22802886 |
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author | Bengus, A Babiuc, RD |
author_facet | Bengus, A Babiuc, RD |
author_sort | Bengus, A |
collection | PubMed |
description | Hyponatremia is a frequent complication of the advanced liver disease, being, as the hepatorenal syndrome, a consequence of the important circulatory dysfunction of cirrhosis. Hyponatremia is determined by the impaired capacity of the kidney to excrete free water, which leads to water retention disproportionate to sodium retention, thus causing low plasma osmolarity. Hyponatremia in cirrhosis is associated with a high morbidity and mortality, its presence suggesting a very advanced liver disease. Current evidence suggests that hyponatremia affects the brain function and predisposes to hepatic encephalopathy. In addition, hyponatremia is a risk factor for liver transplantation, being associated with a high frequency of complication and affecting short and long-term post-transplant survival. |
format | Online Article Text |
id | pubmed-3391887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-33918872012-08-12 Hyponatremia – predictor of adverse prognosis in cirrhosis Bengus, A Babiuc, RD J Med Life General Article Hyponatremia is a frequent complication of the advanced liver disease, being, as the hepatorenal syndrome, a consequence of the important circulatory dysfunction of cirrhosis. Hyponatremia is determined by the impaired capacity of the kidney to excrete free water, which leads to water retention disproportionate to sodium retention, thus causing low plasma osmolarity. Hyponatremia in cirrhosis is associated with a high morbidity and mortality, its presence suggesting a very advanced liver disease. Current evidence suggests that hyponatremia affects the brain function and predisposes to hepatic encephalopathy. In addition, hyponatremia is a risk factor for liver transplantation, being associated with a high frequency of complication and affecting short and long-term post-transplant survival. Carol Davila University Press 2012-06-12 2012-06-18 /pmc/articles/PMC3391887/ /pubmed/22802886 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | General Article Bengus, A Babiuc, RD Hyponatremia – predictor of adverse prognosis in cirrhosis |
title | Hyponatremia – predictor of adverse prognosis in cirrhosis |
title_full | Hyponatremia – predictor of adverse prognosis in cirrhosis |
title_fullStr | Hyponatremia – predictor of adverse prognosis in cirrhosis |
title_full_unstemmed | Hyponatremia – predictor of adverse prognosis in cirrhosis |
title_short | Hyponatremia – predictor of adverse prognosis in cirrhosis |
title_sort | hyponatremia – predictor of adverse prognosis in cirrhosis |
topic | General Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391887/ https://www.ncbi.nlm.nih.gov/pubmed/22802886 |
work_keys_str_mv | AT bengusa hyponatremiapredictorofadverseprognosisincirrhosis AT babiucrd hyponatremiapredictorofadverseprognosisincirrhosis |