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Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

BACKGROUND: Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the present study, we aim to test the effect of all trans retinoic acid (ATRA) on ABC...

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Detalles Bibliográficos
Autores principales:	Jiang, Hong, Badralmaa, Yunden, Yang, Jun, Lempicki, Richard, Hazen, Allison, Natarajan, Ven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391983/ https://www.ncbi.nlm.nih.gov/pubmed/22676378 http://dx.doi.org/10.1186/1476-511X-11-69

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