Cargando…

Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain

BACKGROUND: Neuropathic pain in the trigeminal system is frequently observed in clinic, but the mechanisms involved are largely unknown. In addition, the function of immune cells and related chemicals in the mechanism of pain has been recognized, whereas few studies have addressed the potential role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zhi-Jun, Dong, Yu-Lin, Lu, Ying, Cao, Su, Zhao, Zhi-Qi, Gao, Yong-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391989/ https://www.ncbi.nlm.nih.gov/pubmed/22721162 http://dx.doi.org/10.1186/1742-2094-9-136

Ejemplares similares

Chemokine CCL7 mediates trigeminal neuropathic pain via CCR2/CCR3-ERK pathway in the trigeminal ganglion of mice
por: Zhu, Lin-Peng, et al.
Publicado: (2023)

Microglia and Inhibitory Circuitry in the Medullary Dorsal Horn: Laminar and Time-Dependent Changes in a Trigeminal Model of Neuropathic Pain
por: García-Magro, Nuria, et al.
Publicado: (2021)

Ceftriaxone Relieves Trigeminal Neuropathic Pain Through Suppression of Spatiotemporal Synaptic Plasticity via Restoration of Glutamate Transporter 1 in the Medullary Dorsal Horn
por: Luo, Xiao, et al.
Publicado: (2020)

Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity
por: Dansereau, Marc-André, et al.
Publicado: (2021)

Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain
por: Biber, Knut, et al.
Publicado: (2014)

Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn
por: Heles, Mario, et al.
Publicado: (2021)

Trigeminal Medullary Dorsal Horn Neurons Activated by Nasal Stimulation Coexpress AMPA, NMDA, and NK1 Receptors
por: McCulloch, P. F., et al.
Publicado: (2013)

Somatotopy in the Medullary Dorsal Horn As a Basis for Orofacial Reflex Behavior
por: Panneton, W. Michael, et al.
Publicado: (2017)

Triptolide Attenuates Neuropathic Pain by Regulating Microglia Polarization through the CCL2/CCR2 Axis
por: Bao, Xubin, et al.
Publicado: (2021)

Peripheral Neuropathic Facial/Trigeminal Pain and RANTES/CCL5 in Jawbone Cavitation
por: Lechner, Johann, et al.
Publicado: (2015)

Proteomic Analysis of the Spinal Dorsal Horn in Mice with Neuropathic Pain After Exercise
por: Bai, Jie, et al.
Publicado: (2023)

Electroacupuncture Alleviates Diabetic Neuropathic Pain and Downregulates p-PKC and TRPV1 in Dorsal Root Ganglions and Spinal Cord Dorsal Horn
por: Ma, Yi-qi, et al.
Publicado: (2023)

Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice
por: Zhang, Qian, et al.
Publicado: (2016)

Endoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model
por: Zhang, Enji, et al.
Publicado: (2015)

Levo-Corydalmine Alleviates Neuropathic Cancer Pain Induced by Tumor Compression via the CCL2/CCR2 Pathway
por: Hu, Yahui, et al.
Publicado: (2017)

Screening and Identification of Key Genes, Pathways, and Drugs Associated with Neuropathic Pain in Dorsal Horn: Evidence from Bioinformatic Analysis
por: Yang, Xiao, et al.
Publicado: (2021)

Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission
por: Zhang, Kun-Long, et al.
Publicado: (2021)

TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice
por: Zhao, Lin-Xia, et al.
Publicado: (2020)

Downregulation of nuclear STAT2 protein in the spinal dorsal horn is involved in neuropathic pain following chronic constriction injury of the rat sciatic nerve
por: Huang, Zhifeng, et al.
Publicado: (2023)

Glycinergic dysfunction in a subpopulation of dorsal horn interneurons in a rat model of neuropathic pain
por: Imlach, Wendy L., et al.
Publicado: (2016)

Effects of metformin on the expression of AMPK and STAT3 in the spinal dorsal horn of rats with neuropathic pain
por: Ge, Anqi, et al.
Publicado: (2018)

Functional Reorganization of Local Circuit Connectivity in Superficial Spinal Dorsal Horn with Neuropathic Pain States
por: Gong, Nian, et al.
Publicado: (2019)

Hypoxia-induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain
por: Da Vitoria Lobo, Marlene E., et al.
Publicado: (2022)

The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity
por: Scheu, Stefanie, et al.
Publicado: (2017)

Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn
por: Zheng, Xiao-bo, et al.
Publicado: (2019)

Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats
por: Miyakawa, Tsuyoshi, et al.
Publicado: (2014)

Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis
por: Yogo, Yurika, et al.
Publicado: (2009)

Chemokines and Pain in the Trigeminal System
por: Solis-Castro, Oscar O., et al.
Publicado: (2021)

Synaptic Connections of the Neurokinin 1 Receptor-Like Immunoreactive Neurons in the Rat Medullary Dorsal Horn
por: Qi, Jian, et al.
Publicado: (2011)

Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain
por: Masuda, Takahiro, et al.
Publicado: (2016)

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn
por: Nelson, Tyler S., et al.
Publicado: (2019)

Systemic Injection of Thalidomide Prevent and Attenuate Neuropathic Pain and Alleviate Neuroinflammatory Response in the Spinal Dorsal Horn
por: Xu, Hao, et al.
Publicado: (2019)

Z-Guggulsterone Relieves Neuropathic Pain by Inhibiting the Expression of Astrocytes and Proinflammatory Cytokines in the Spinal Dorsal Horn
por: Dang, Sha-Jie, et al.
Publicado: (2022)

Activation of the bile acid receptors TGR5 and FXR in the spinal dorsal horn alleviates neuropathic pain
por: Wu, Yuning, et al.
Publicado: (2023)

Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment
por: Honda, Kuniya, et al.
Publicado: (2008)

Suppression of microglial Ccl2 reduces neuropathic pain associated with chronic spinal compression
por: Li, Quan, et al.
Publicado: (2023)

Pharmacological Evidence of the Important Roles of CCR1 and CCR3 and Their Endogenous Ligands CCL2/7/8 in Hypersensitivity Based on a Murine Model of Neuropathic Pain
por: Pawlik, Katarzyna, et al.
Publicado: (2022)

Inhibition of NKCC1 in spinal dorsal horn and dorsal root ganglion results in alleviation of neuropathic pain in rats with spinal cord contusion
por: Wu, Yao, et al.
Publicado: (2023)

Functional expression of CCL8 and its interaction with chemokine receptor CCR3
por: Ge, Baosheng, et al.
Publicado: (2017)

The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
por: Rizeq, Balsam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h80k1d9evm34qig1r6u8c1ap2b