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Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes

BACKGROUND: Hepatic gluconeogenesis tightly controls blood glucose levels in healthy individuals, yet disorders of fatty acids (FAs) oxidation are characterized by hypoglycemia. We studied the ability of free-FAs to directly inhibit gluconeogenesis, as a novel mechanism that elucidates the hypoglyce...

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Detalles Bibliográficos
Autores principales:	Budick-Harmelin, Noga, Anavi, Sarit, Madar, Zecharia, Tirosh, Oren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391994/ https://www.ncbi.nlm.nih.gov/pubmed/22676303 http://dx.doi.org/10.1186/1476-511X-11-66

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