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Parkinson’s disease and immune system: is the culprit LRRKing in the periphery?
Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain kinase/GTPase that has been recently linked to three pathological conditions: Parkinson’s disease; Crohn’s disease; and leprosy. Although LRRK2 physiological function is poorly understood, a potential role in inflammatory response is sugges...
Autores principales: | Greggio, Elisa, Civiero, Laura, Bisaglia, Marco, Bubacco, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391996/ https://www.ncbi.nlm.nih.gov/pubmed/22594666 http://dx.doi.org/10.1186/1742-2094-9-94 |
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