Formulation, characterization, and evaluation of in vitro skin permeation and in vivo pharmacodynamics of surface-charged tripterine-loaded nanostructured lipid carriers

BACKGROUND: Nanostructured lipid carriers (NLCs) are attractive materials for topical drug delivery, and in a previous study, we demonstrated that NLCs loaded with tripterine enhance its deposition. However, the surface charge of nanoparticles influences percutaneous drug penetration. Therefore, we...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Zhou, Lei, Yuan, Ling, Zhang, Zhen-hai, Liu, Xuan, Wu, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392146/
https://www.ncbi.nlm.nih.gov/pubmed/22787398
http://dx.doi.org/10.2147/IJN.S32476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392146/
https://www.ncbi.nlm.nih.gov/pubmed/22787398
http://dx.doi.org/10.2147/IJN.S32476

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