Ultrasound-targeted transfection of tissue-type plasminogen activator gene carried by albumin nanoparticles to dog myocardium to prevent thrombosis after heart mechanical valve replacement

BACKGROUND: There are more than 300,000 prosthetic heart valve replacements each year worldwide. These patients are faced with a higher risk of thromboembolic events after heart valve surgery and long-term or even life-long anticoagulative and antiplatelet therapies are necessary. Some severe compli...

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Detalles Bibliográficos
Autores principales: Ji, Jun, Ji, Shang-Yi, Yang, Jian-An, He, Xia, Yang, Xiao-Han, Ling, Wen-Ping, Chen, Xiao-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392147/
https://www.ncbi.nlm.nih.gov/pubmed/22787391
http://dx.doi.org/10.2147/IJN.S32363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392147/
https://www.ncbi.nlm.nih.gov/pubmed/22787391
http://dx.doi.org/10.2147/IJN.S32363

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