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MIP-1δ Activates NFATc1 and Enhances Osteoclastogenesis: Involvement of Both PLCγ2 and NFκB Signaling

Pathological bone resorption is a source of significant morbidity in diseases affecting the skeleton such as rheumatoid arthritis, periodontitis, and cancer metastasis to bone. Evidence indicates that elevated levels of inflammatory mediators such as IL-1, IL-6, and TNF-α play a role in this process...

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Detalles Bibliográficos
Autores principales:	Weber, Kristy L., Doucet, Michele, Shaner, Adam, Hsu, Nigel, Huang, David, Fogel, Jenna, Kominsky, Scott L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392212/ https://www.ncbi.nlm.nih.gov/pubmed/22792407 http://dx.doi.org/10.1371/journal.pone.0040799

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