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Cyclosporine Treatment Reduces Oxygen Free Radical Generation and Oxidative Stress in the Brain of Hypoxia-Reoxygenated Newborn Piglets
Oxygen free radicals have been implicated in the pathogenesis of hypoxic-ischemic encephalopathy. It has previously been shown in traumatic brain injury animal models that treatment with cyclosporine reduces brain injury. However, the potential neuroprotective effect of cyclosporine in asphyxiated n...
Autores principales: | Gill, Richdeep S., Lee, Tze-Fun, Liu, Jiang-Qin, Chaudhary, Hetal, Brocks, Dion R., Bigam, David L., Cheung, Po-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392221/ https://www.ncbi.nlm.nih.gov/pubmed/22792343 http://dx.doi.org/10.1371/journal.pone.0040471 |
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